Matrixyl 10% + HA: How to Layer It With Other Serums
By The Ordinary | Clinical Formulations with Integrity | Published: 2026-10-18
Category: How-to Guides
Learn the correct order to layer Matrixyl 10% + HA with other serums, including niacinamide, to boost firmness and target fine lines without pilling.
Quick Answer
Layer Matrixyl 10% + HA after cleansing and before heavier creams, and apply niacinamide after it if you use both.
Why Layering Order Matters
The order you apply serums affects how well they absorb and how they feel on your skin. Water-based serums like Matrixyl 10% + HA should go on before thicker, oil-based products. This lets the lightweight formula sink in and work on fine lines and firmness without being blocked by heavier layers.
Matrixyl 10% + HA is a water-based serum, so it sits comfortably under moisturizers and sunscreens. If you use other water-based serums, apply the thinnest first, but you can also alternate layers if you prefer. The key is to let each layer dry slightly before adding the next.
Pairing With Niacinamide: What to Know
You can use Matrixyl 10% + HA and niacinamide together. Niacinamide supports the skin barrier and helps with oil control, while Matrixyl targets fine lines. They work well in the same routine, but the order matters: apply Matrixyl first, then niacinamide. This is because niacinamide can be slightly more irritating when applied to damp skin, so letting the first layer dry reduces that risk.
If you’re new to either ingredient, start by using them on alternate days to see how your skin responds. This helps you avoid overloading your skin and lets you identify which product is working.
Step-by-Step Layering Guide
- Start with clean, dry skin: Wash your face and pat it dry. Apply Matrixyl 10% + HA to clean skin, either directly or after a toner. A common mistake is applying on damp skin, which can dilute the serum and reduce its effectiveness. Wait until your skin is fully dry before applying the serum.
- Apply Matrixyl 10% + HA: Dispense a few drops and press gently into your face and neck. Use it in the morning or evening, but always follow with sunscreen during the day. Avoid rubbing too hard, as this can cause irritation. Use a pea-sized amount for the whole face to avoid waste.
- Wait 30 seconds before the next layer: Let the serum absorb for about 30 seconds. Then apply your next water-based serum, like niacinamide, if you use one. This prevents pilling and ensures each layer absorbs properly. If you notice pilling, you may be applying too much or not waiting long enough.
- Finish with moisturizer and SPF: Lock in the serums with a moisturizer. In the morning, finish with sunscreen. At night, you can skip SPF. A common mistake is skipping moisturizer, which can leave your skin feeling tight and reduce the serum’s benefits. Always use SPF during the day to protect your skin and enhance the anti-aging benefits.
Product Spotlight
- Matrixyl 10% + HA: Matrixyl 10% + HA is a lightweight serum formulated with 10% Matrixyl and Hyaluronic Acid to target fine lines and improve skin firmness. Its lightweight texture makes it easy to layer under other products without feeling heavy, so you can pair it with niacinamide or moisturizer without pilling.
Matrixyl 10% + HA
