How to Layer Multi-Peptide and Copper Peptides Serum
By The Ordinary | Clinical Formulations with Integrity | Published: 2026-10-20
Category: How-to Guides
Learn the correct order for layering Multi-Peptide and Copper Peptides Serum with other skincare steps, plus common mistakes to avoid.
Quick Answer
Apply Multi-Peptide + Copper Peptides 1% Serum after water-based toners and before heavier creams or oils, using a few drops on clean, dry skin.
Why Order Matters
Layering skincare in the right order ensures each product can absorb and work effectively. Peptide serums are water-based and should be applied early, but after any exfoliating or treatment toners, to maximize their benefits.
Common Mistakes
One common mistake is applying peptide serum over heavy creams or oils, which can block absorption. Another is using it immediately after strong acids or retinoids without waiting, which may cause irritation.
Step-by-Step Layering Guide
- Cleanse and dry: Start with a clean face. Pat your skin dry with a towel—do not rub. Applying peptide serum on damp skin can dilute it and reduce effectiveness. Wait a few minutes after cleansing to ensure skin is fully dry.
- Apply toners or exfoliants first: If you use a toner or exfoliating product (like a BHA or AHA), apply it before the peptide serum. Wait for it to absorb completely, usually 1–2 minutes. Never layer acids directly with peptides without waiting, as this can cause irritation.
- Apply Multi-Peptide + Copper Peptides 1% Serum: Dispense a few drops onto your fingers and press gently onto your face and neck. Avoid rubbing vigorously. Let it absorb for 1–2 minutes before moving on. Do not mix with other serums in your palm—apply separately to ensure even coverage.
- Follow with moisturizer: Once the serum has absorbed, apply your moisturizer to lock in hydration and support the skin barrier. This helps keep the peptides working effectively. Choose a moisturizer that suits your skin type—gel for oily, cream for dry.
- Finish with SPF (morning): In the morning, always finish with a broad-spectrum sunscreen. Peptides do not increase sun sensitivity, but sun protection is essential for overall skin health and anti-aging. Apply SPF as the last step of your morning routine, and reapply during the day.
Product Spotlight
- Multi-Peptide + Copper Peptides 1% Serum: Multi-Peptide + Copper Peptides 1% Serum features a blend of multi-peptides and copper peptides for targeted age-supporting benefits. This serum is designed to support skin structure and provide antioxidant protection, making it a versatile addition to a daily routine.

Multi-Peptide + Copper Peptides 1% Serum
Now that you know the correct order, you can confidently incorporate this peptide serum into your routine. Start with a patch test if you are new to copper peptides, and adjust frequency based on your skin's response.
